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Please note, this article may not be in plain English. It has been written for health care professionals and researchers.

I've tried a lot of supplements over the years trying to find something that can help me with my asperger's/social anxiety. I feel obligated to tell you guys about sulforaphane because I've had great results with it.

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Can Activation of NRF2 Be a Strategy against COVID-19?” published in Trends in Pharmacological Sciences Make sure you take the equivalent of 15-25 mg (or 9-27 mg if you want to go by the research). I had zero noticable effects from taking 5-10 mg (usually one capsule). When I upped my dose, I noticed effects within 3 days. If you do choose this route, how much should you eat? Well, you could easily consume a couple [of] ounces a day to get really good benefit, but that’s going to involve a lot of sprouting. For reference, if you go out and buy a clamshell container of sprouts at the grocery store, that’s about four ounces. Eating two ounces of sprouts today is quite a lot of sprouts. You can put them in salads or smoothies or just eat them straight. In some of the studies on sulforaphane, the researchers actually processed the sprouts into a beverage and asked people to drink the beverage because they felt that was more feasible than asking people to eat two to four ounces of sprouts every day. So there’s no right or wrong answer there. The answer might be as much as you can tolerate and as much as you’re able to make in a sustainable way. Step-by-Step Tutorial on How to Make Broccoli Sprouts So we’ve covered why sulforaphane might be of interest, and the different forms that Rhonda takes it in.

Consuming sulforaphane in amounts found in cruciferous vegetables is considered safe with few — if any — side effects ( 8). In Jed’s studies using Moringa, participants consumed it as a cold-brewed tea. This can be made by adding moringa to room temperature water and leaving to stand for at least 10 minutes. They suggest a ratio of 1:100, powder to water. So for example: The last sulforaphane supplement that has been tested by Jed Fahey and his team is Thorne’s Crucera-SGS. This contains glucoraphanin (sulforaphane glucosinolate, or SGS), but doesn’t contain the additional myrocinase enzyme. Interestingly, our guts do contain bacteria that convert glucoraphanin into sulforaphane. The amounts vary from person to person, and aren’t as optimal as consuming additional active myrocinase.

Materials and Methods

No, sulforaphane isn’t associated with weight gain. On the contrary, studies in mice have shown it may even prevent weight gain. Is It Safe to Take Sulforaphane Supplements Long-Term? Sulforaphane and DIM (di-indolyl methane) are plant compounds found in cruciferous vegetables. They’re both potent antioxidants with anticancer properties. We need more research to find out the best dose of sulforaphane for different health goals. How Long Does Sulforaphane Take to Work? The last bonus benefit I want to talk about is related to COVID-19. A paper published almost a year ago in July 2020 posed the question, can activation of Nrf2 be a strategy against COVID-19? It pointed out that COVID-19 is characterized by an out of control inflammatory response, including a cytokine storm and a loss of T-lymphocytes. The authors speculated that an anti-inflammatory strategy characterized by Nrf2 could restore redox and protein homeostasis, promote resolution of inflammation, and facilitate tissue repair. They pointed out that sulforaphane is already being studied for these effects against COVID-19 in clinical trials. As far as I know, at the time of this recording in June 2021, none of these trials has been published yet. So we don’t have results. Having said that, given sulforaphane’s well-established effect of stimulating Nrf2 and Nrf2’s well-established anti-inflammatory role, it stands to reason that sulforaphane may have some protective effect in cases of COVID-19. Eating just 10 grams of broccoli sprout powder per day may improve insulin resistance. Insulin is the pancreatic hormone that pushes sugar from your bloodstream into your cells. The more responsive your cells are to insulin, the better your blood sugar levels.